Greatest Loss
To loose money, prestige, health or even life itself is not such a loss. To loose faith is the greatest loss.
Negative Aspect of Sex
Sex could be a gift of God but when it becomes an obsession, it blunders all intelligence and people are driven to abominable acts to satisfy their lust.
Paramatma
The Paramatma is always the caitya-guru, the spiritual master within. He comes before one externally as the instructor and initiator (Siksa and Diksa Guru).
Frustration
A materialistic person, thinking himself very advanced in intelligence, continuously acts for economic development. But again and again, as enunciated in the Vedas, he is frustrated by material activities, either in this life or in the next. Indeed, the results one obtains are inevitably the opposite of those one desires.