Nobody is free from anxiety. The soul is suffering & that is expressed through the manifested body.
Even in the womb of the mother you will suffer. To remain in that compact bag for so many months, hands and legs all tied up, unable to move this is suffering. So we should be intelligent enough to ask, "Why am I suffering? and how can I stop this suffering?"
We act according to our whims and the resultant action is there immediately. Nature's law, God's law, is there. It is not God's creation that somebody is suffering from some painful condition and somebody is enjoying. No. We infect ourselves with some contamination because this material world is full of contamination. You must remain very cautious. Otherwise you will have to suffer. — Conversation in Mayapur, 19th Mar, 1976.
The sufferings of humanity are due to forgetfulness of Krishna as the supreme enjoyer, the supreme proprietor and the supreme friend. Therefore, to act to revive this consciousness within the entire human society is the highest welfare work. One cannot be engaged in such first-class welfare work without being liberated.
The flip side of happiness is suffering.
Anyone who inflicts pain upon others suffers himself from that pain. Lord Buddha said that you are not punished for your anger, you are punished by your anger.