To attain freedom from material life, one must take to Krishna consciousness.
Srimad Bhagavatam 6.5.16,
Life doesn't come from matter. Matter is generated from life.
Science of Self Realization,
One thing is certain – Uncertainty of our life.
The real problem of life in the material world is to solve the question of birth, death, old age and disease.
Srimad Bhagavatam 2.3.2-7,