Krishna is the supreme father and all living entities within the material world are exactly like misled children of a wealthy man who has left home to loiter in the street. Therefore the greatest benefit one can bestow upon one's fellow human being is to give him Krishna consciousness.
One who always sees all living entities as spiritual sparks, in quality, one with the Lord, becomes a true knower of things. What, then, can be illusion or anxiety for him?
Any jiva, in any form of life, in the form of a Bird or Animal, or in the form of a Human, can become a Devotee.
The living entities are not actually meant to be under the control of the modes but when they reject Krishna then they become affected by the three modes of material nature and as a result of that they identify themselves with the material nature.
To give and take affection is a natural craving for every living entity.