This is the divinity of the Personality of Godhead: He is not affected by the qualities of material nature, even though he is in contact with them. Similarly, the devotees who have taken shelter of the Lord do not become influenced by the material qualities.
Krishna and pure devotees see through the substance, not the maya the world sees through.
God controls the material as well as the spiritual, which means that everything directly or indirectly happens through the sanction of the Lord. If we can just accept that our circumstances are meant to benefit us, we will be able to connect with the loving aspect of the Lord and learn to grow from a seemingly negative situation.
You have to be a complete fool to not accept the existence of God.
Lecture on "Memories of my youth" – 27th OCT'06 – DXB